Hydrochloric Acid → N-[1-(1-acetylpiperidine-4-carbonyl)-3-(4-fluoro-2-methylphenyl)piperidin-4-yl]-N-methyl-3,5-bis(trifluoromethyl)benzamide

HRID 142329

Reaction equation

HRID 142329 reaction equation
[C:34]([CH3:35])(=[O:36])[N:37]1[CH2:38][CH2:39][CH:40]([C:43](=[O:44])[OH:45])[CH2:41][CH2:42]1.[ClH:1].[F:2][c:3]1[cH:4][c:5]([CH3:33])[c:6]([CH:9]2[CH2:10][NH:11][CH2:12][CH2:13][CH:14]2[N:15]([C:16]([c:17]2[cH:18][c:19]([C:27]([F:28])([F:29])[F:30])[cH:20][c:21]([C:23]([F:24])([F:25])[F:26])[cH:22]2)=[O:31])[CH3:32])[cH:7][cH:8]1>>[F:2][c:3]1[cH:4][c:5]([CH3:33])[c:6]([CH:9]2[CH2:10][N:11]([C:43]([CH:40]3[CH2:39][CH2:38][N:37]([C:34]([CH3:35])=[O:36])[CH2:42][CH2:41]3)=[O:44])[CH2:12][CH2:13][CH:14]2[N:15]([C:16]([c:17]2[cH:18][c:19]([C:27]([F:28])([F:29])[F:30])[cH:20][c:21]([C:23]([F:24])([F:25])[F:26])[cH:22]2)=[O:31])[CH3:32])[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 1172551-Acetylpiperidine-4-carboxylic acidHCID 87628497N-[3-(4-fluoro-2-methylphenyl)piperidin-4-yl]-N-methyl-3,5-bis(trifluoromethyl)benzamide

Product 1

HCID 87628049N-[1-(1-acetylpiperidine-4-carbonyl)-3-(4-fluoro-2-methylphenyl)piperidin-4-yl]-N-methyl-3,5-bis(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-ec61f88606bb4b4cb9b6491f10efef3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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