Bromomethylcyclopropane → 1185836-83-2

Reaction equation

[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([O:9][CH3:10])=[CH:4][C:3]=1[OH:11].Br[CH2:13][CH:14]1[CH2:16][CH2:15]1>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([O:9][CH3:10])=[CH:4][C:3]=1[O:11][CH2:13][CH:14]1[CH2:16][CH2:15]1

Participants

Reactant 2

HCID 81503Bromomethylcyclopropane

HCID 668669282-bromo-4-fluoro-5-methoxyPhenol

Product 1

HCID 568468981185836-83-2

Procedure

Starting from 2-bromo-4-fluoro-5-methoxy-phenol (example B.a2) and commercially available bromomethyl-cyclopropane the title compound is obtained as colorless solid.

Sources & evidence

ORD record: ord-0e5e4a6625884a8f84bc1241dff6e19e
Source dataset: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08927557B2

Reaction notes

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