1-Hydroxybenzotriazole → tert-Butyl cis(+/-)-3-(4-{[(5-Ethyl-4-trifluoromethyl-1H-imidazol-2-yl)carbonyl]amino}-3-ethoxypiperidin-1-yl)benzoate

Reaction equation

[NH2:1][C@H:2]1[CH2:7][CH2:6][N:5]([C:8]2[CH:9]=[C:10]([CH:18]=[CH:19][CH:20]=2)[C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[CH2:4][C@H:3]1[O:21][CH2:22][CH3:23].[CH2:24]([C:26]1[NH:30][C:29]([C:31](O)=[O:32])=[N:28][C:27]=1[C:34]([F:37])([F:36])[F:35])[CH3:25].CCN=C=NCCCN(C)C.Cl.C1C=CC2N(O)N=NC=2C=1>>[CH2:24]([C:26]1[NH:30][C:29]([C:31]([NH:1][C@H:2]2[CH2:7][CH2:6][N:5]([C:8]3[CH:9]=[C:10]([CH:18]=[CH:19][CH:20]=3)[C:11]([O:13][C:14]([CH3:16])([CH3:17])[CH3:15])=[O:12])[CH2:4][C@H:3]2[O:21][CH2:22][CH3:23])=[O:32])=[N:28][C:27]=1[C:34]([F:36])([F:37])[F:35])[CH3:25]