Magnesium ethanolate → HCID 178525631, compound
Reaction equation
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([O-:5])=[O:4].[O-]CC.[Mg+2:13].[O-]CC>C1COCC1>[C:1]([O-:7])(=[O:6])[CH2:2][C:3]([O-:5])=[O:4].[CH2:8]([Mg+2:13])[CH3:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a stirred solution of monoethyl malonate 1(1.65 g, 12.5 mmol) in THF (25 mL) was added the magnesium ethoxide (0.61 g, 6.25 mmol). The reaction mixture was allowed to stir at rt for 5 h (until the solution become clear). The result solution was used for next step without any treatment.
Sources & evidence
- ORD record
- ord-6bf30d76f105458abf336a2d91aa06a1
- Source dataset
- uspto-grants-2015_01
- Patent number
- US08940506B2
Reaction notes
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