Mupirocin → ZE7Qpy4258
Reaction equation
CC1(C)S[C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13](N)[C:14]3[CH:15]=[CH:16][C:17](O)=[CH:18][CH:19]=3)=O)[C:8](=O)N2[C@H]1C(O)=O.[CH2:26]1C(=O)[N:28]2[C@@H](C([O-])=O)/C(/O[C@H:27]12)=C/CO.[K+].C[C@@H:42]([C@@H](O)C)[C@@H:43]1O[C@H:44]1[CH2:46][C@@H:47]1[C@@H](O)[C@@H:51](O)[C@H:50]([CH2:55]/[C:56](/[CH3:72])=C/C(OCCCCCCCCC(O)=O)=O)[O:49][CH2:48]1.[CH:76]1C(NC(NC(NCCCCCCNC(NC(NC2C=CC(Cl)=CC=2)=N)=N)=N)=N)=CC=C(Cl)[CH:77]=1.C(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O>>[CH3:26][C:27]1[C:5]2[CH2:76][CH2:77][N:10]([CH2:11][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:7]=2[C:8]2[CH:51]=[C:50]([O:49][C:48]3[CH:42]=[CH:43][CH:44]=[CH:46][CH:47]=3)[CH:55]=[CH:56][C:72]=2[N:28]=1Participants
4
Procedure
Co-amoxiclav (1000/200 mg infusion, GlaxoSmithKline) was purchased from St George's NHS Hospital, London. Mupirocin was purchased from Sigma Aldrich Ltd (Poole, Dorset, UK). Chlorhexidine gluconate was purchased from Sigma Aldrich Ltd (Poole, Dorset, UK). 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline (in hydrochloride salt form) was provided by Helperby Therapeutics.