Ethylene Oxide → 3-Bromo-4-(3-hydroxypropyl)pyridine

HRID 143180

Reaction equation

HRID 143180 reaction equation
[Br:19][c:20]1[cH:21][n:22][cH:23][cH:24][c:25]1[CH3:26].[CH2:27]1[CH2:28][O:29]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7]>>[Br:19][c:20]1[cH:21][n:22][cH:23][cH:24][c:25]1[CH2:26][CH2:27][CH2:28][OH:29]

Participants

7

Reactant 6

HCID 6354Ethylene OxideHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 8058HexaneHCID 8176303-Bromo-4-methylpyridineHCID 178418339Butyllithium

Product 1

HCID 117905953-Bromo-4-(3-hydroxypropyl)pyridine

Sources & evidence

ORD record
ord-d584de915e424f269e244eb097e7d0f5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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