Hydrochloric Acid → Allylethylamine
Reaction equation
C(OC(=O)[N:7]([CH2:10][CH:11]=[CH2:12])[CH2:8][CH3:9])(C)(C)C.[ClH:14]>O1CCOCC1>[ClH:14].[CH2:10]([NH:7][CH2:8][CH3:9])[CH:11]=[CH2:12].[CH2:10]([NH:7][CH2:8][CH3:9])[CH:11]=[CH2:12]Participants
5
Reactant 2
Product 2
Reagents, catalysts & solvents 1
Procedure
At 10° C. 28.9 g allyl-ethyl-carbamic acid tert-butyl ester (156 mmol) are dissolved in 200 ml 4N HCl in dioxane and slowly warmed to room temperature. When the development of gas has ceased the mixture is warmed at 30° C. for 1 h. The mixture is concentrated under reduced pressure and crystallized from EtOH/TBME to yield the hydrochloric acid salt of allyl ethyl amine as white plates.
Workup
- customAt 10° C
- temperatureis warmed at 30° C. for 1 h
- concentrationThe mixture is concentrated under reduced pressure
- customcrystallized from EtOH/TBME
Sources & evidence
- ORD record
- ord-a80a7843777b4623b4f0803942946845
- Source dataset
- uspto-grants-2009_11
- Patent number
- US07612055B2
Reaction notes
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