Lithium ion → 1-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}4-methylpiperazine

Reaction equation

[Al+3:25].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:9]2([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][N:20]([CH3:23])[CH2:21][CH2:22]3)[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[cH:7][cH:8]1.[H-:24].[H-:27].[H-:28].[H-:29].[Li+:26]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:15][N:17]3[CH2:18][CH2:19][N:20]([CH3:23])[CH2:21][CH2:22]3)[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[cH:7][cH:8]1

Participants

Reactant 4

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 16415282(4-Methyl-1-piperazinyl)[tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methanone

Product 1

HCID 685756701-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}4-methylpiperazine

Sources & evidence

ORD record: ord-c6648efdd8974db6a1f1321946cf649f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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