Diethyl Oxalate → HCID 57940661, compound

Reaction equation

[CH3:1][S:2][C:3]1[CH:8]=[CH:7][N:6]=[C:5]([C:9](=[O:11])[CH3:10])[CH:4]=1.[C:12](OCC)(=[O:18])[C:13]([O:15][CH2:16][CH3:17])=[O:14]>>[CH2:16]([O:15][C:13](=[O:14])[C:12](=[O:18])[CH2:10][C:9]([C:5]1[CH:4]=[C:3]([S:2][CH3:1])[CH:8]=[CH:7][N:6]=1)=[O:11])[CH3:17]

Participants

Reactant 2

HCID 7268Diethyl Oxalate

HCID 230903331-(4-Methylthio-2-pyridyl)ethanone

Product 1

HCID 57940661HCID 57940661, compoundYield 58%

Procedure

The general procedure of Referential Example 17 was repeated through use of 1-(4-methylthio-2-pyridyl)ethanone (1.76 g) and diethyl oxalate (2.86 mL), to thereby give the title compound as a solid (1.64 g, 58%).

Sources & evidence

ORD record: ord-e2ffa235edbb4870aafe1dbad87af889
Source dataset: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07622471B2

Reaction notes

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