Sodium ion → 4-cyclopropyl-N-[3-methyl-5-(1,3-thiazol-5-yl)phenyl]pyrimidin-2-amine

HRID 143804Notes

Reaction equation

HRID 143804 reaction equation
[Br:27][c:28]1[cH:29][n:30][cH:31][s:32]1.[CH3:39][CH:40]1[CH2:41][CH2:42][CH2:43][O:44]1.[CH:1]1([c:4]2[n:5][c:6]([NH:10][c:11]3[cH:12][c:13]([CH3:26])[cH:14][c:15]([B:17]4[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]4)[cH:16]3)[n:7][cH:8][cH:9]2)[CH2:2][CH2:3]1.[Na+:33].[Na+:34].[O-:35][C:36](=[O:37])[O-:38]>>[CH:1]1([c:4]2[n:5][c:6]([NH:10][c:11]3[cH:12][c:13]([CH3:26])[cH:14][c:15](-[c:28]4[cH:29][n:30][cH:31][s:32]4)[cH:16]3)[n:7][cH:8][cH:9]2)[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 73012-MethyltetrahydrofuranHCID 19660Carbonate IonHCID 5460595-BromothiazoleHCID 67256390HCID 67256390, compound

Product 1

HCID 584561394-cyclopropyl-N-[3-methyl-5-(1,3-thiazol-5-yl)phenyl]pyrimidin-2-amine

Sources & evidence

ORD record
ord-c951245706e649ceb32b8920ae7202de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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