Hydrochloric Acid → Ethyl 2-(2-methyl-3,5-dioxo-1,2,4-thiadiazolidin-4-yl)acetate

HRID 1445665

Reaction equation

[N:1]([CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])=[C:2]=[S:3].Cl.[O-:11][Mn](=O)(=O)=O.[K+].[CH3:17][N:18]=[C:19]=[O:20]>>[CH2:8]([O:7][C:5]([CH2:4][N:1]1[C:2](=[O:11])[S:3][N:18]([CH3:17])[C:19]1=[O:20])=[O:6])[CH3:9]

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 12228Methyl Isocyanate

HCID 32202Acetic acid, 2-isothiocyanato-, ethyl ester

HCID 516875Potassium Permanganate

Product 1

HCID 6539175Ethyl 2-(2-methyl-3,5-dioxo-1,2,4-thiadiazolidin-4-yl)acetate

Procedure

Reagents: Ethyl isothiocyanatoacetate (0.8 ml, 6.5 mmol), 35% HCl (3.1 ml), KMnO4 (0.5 g), methyl isocyanate (0.38 ml, 6.5 mmol).

Sources & evidence

ORD record: ord-467a88bc84c1476b92a27935ed85a954
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07666885B2

Linked notes

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