Dichloromethane → 2'-Fluoro-3-methyl-N-[5-(2-pyrazinyl)-2-pyridinyl][2,4'-bipyridine]-5-acetamide

HRID 144626

Reaction equation

HRID 144626 reaction equation
[CH:32]([N:33]=[C:34]=[N:35][CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:41][CH2:42][Cl:43].[F:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][cH:10][c:11]([CH2:15][C:16](=[O:17])[OH:18])[cH:12][c:13]2[CH3:14])[cH:7]1.[n:19]1[c:20](-[c:25]2[cH:26][cH:27][c:28]([NH2:31])[n:29][cH:30]2)[cH:21][n:22][cH:23][cH:24]1>>[F:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][cH:10][c:11]([CH2:15][C:16](=[O:18])[NH:31][c:28]3[cH:27][cH:26][c:25](-[c:20]4[n:19][cH:24][cH:23][n:22][cH:21]4)[cH:30][n:29]3)[cH:12][c:13]2[CH3:14])[cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 12734DiisopropylcarbodiimideHCID 584476922-(2'-Fluoro-3-methyl-2,4'-bipyridin-5-yl)acetic acidHCID 592592255-(Pyrazin-2-yl)pyridin-2-amine

Product 1

HCID 469273642'-Fluoro-3-methyl-N-[5-(2-pyrazinyl)-2-pyridinyl][2,4'-bipyridine]-5-acetamide

Sources & evidence

ORD record
ord-fd0d32fb14d94e37b1fdbdaabd0faf37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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