3-Bromo-4-Methyl-5-Nitropyridine → 5-Bromo-4-methylpyridin-3-amine

HRID 1454939Notes

Reaction equation

HRID 1454939 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([N+:9]([O-])=O)[C:7]=1[CH3:8]>[Fe]>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([NH2:9])[C:7]=1[CH3:8]

Participants

3

Reactant 1

HCID 125100543-Bromo-4-Methyl-5-Nitropyridine2×

Product 1

HCID 70606795-Bromo-4-methylpyridin-3-amine

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

This compound is obtained by reducing 3-bromo-4-methyl-5-nitropyridine (Intermediate 29.5) with iron in a manner similar to the synthesis of Intermediate 29.7, on the scale of 10 mmol.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-bc2e76c04cb44cb2b9ffaf63685fbd41
Source dataset
uspto-grants-2009_01
Patent number
US07482342B2

Reaction notes

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