Piperidin-4-ol → 1-[3-(4-Morpholin-4-yl-but-1-ynyl)-benzyl]-piperidin-4-ol

HRID 1455181Notes

Reaction equation

HRID 1455181 reaction equation
[N:1]1([CH2:7][CH2:8][C:9]#[C:10][C:11]2[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=2)[CH:14]=O)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH:19]1[CH2:24][CH2:23][CH:22]([OH:25])[CH2:21][CH2:20]1>>[N:1]1([CH2:7][CH2:8][C:9]#[C:10][C:11]2[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=2)[CH2:14][N:19]2[CH2:24][CH2:23][CH:22]([OH:25])[CH2:21][CH2:20]2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 224934723-(4-Morpholin-4-yl-but-1-ynyl)-benzaldehyde

Product 1

HCID 102865791-[3-(4-Morpholin-4-yl-but-1-ynyl)-benzyl]-piperidin-4-ol

Procedure

May be prepared analogously to Example 15 using the product of Example 10 and piperidin-4-ol.

Sources & evidence

ORD record
ord-307959d74e1b41b9ad367641be8e8993
Source dataset
uspto-grants-2009_01
Patent number
US07482364B2

Reaction notes

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