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3-Nitrobenzaldehyde → ((2(S)-Benzoylamino-3-methylbutyryl)-(3-nitrobenzyl)amino)acetic Acid Ethyl Ester

HRID 1456668
Notes
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Reaction equation

HRID 1456668 reaction equation
[CH2:1]([O:3][C:4](=[O:29])[CH2:5][N:6]([C:14](=[O:28])[C@@H:15]([NH:19][C:20](=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH:16]([CH3:18])[CH3:17])[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH3:2].[N+:30](C1C=C(C=CC=1)C=O)([O-:32])=[O:31].C(OC(=O)CNCC1C=CC=CC=1)C>>[CH2:1]([O:3][C:4](=[O:29])[CH2:5][N:6]([C:14](=[O:28])[C@@H:15]([NH:19][C:20](=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH:16]([CH3:18])[CH3:17])[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([N+:30]([O-:32])=[O:31])[CH:9]=1)[CH3:2]
ParticipantsProcedureSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 74493-NitrobenzaldehydeHCID 80908N-Benzylglycine ethyl esterHCID 53936603((2(S)-Benzoylamino-3-methylbutyryl)benzylamino)acetic Acid Ethyl Ester

Product 1

HCID 54107516((2(S)-Benzoylamino-3-methylbutyryl)-(3-nitrobenzyl)amino)acetic Acid Ethyl Ester

Procedure

Compound 734 was prepared by a method similar to the method used to prepare compound 703 except benzaldehdye was replaced with 3-nitrobenzaldehyde in the preparation of 701. ##STR113##

Sources & evidence

ORD record
ord-9f512b20acf8460296cead7c096b81b1
Source dataset
uspto-grants-1998_12
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US05843904

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes