Hydrochloric Acid → HCID 22097029, compound
Reaction equation
[Cl:1][C:2]1[C:3]([N:17]([CH3:23])[S:18]([CH2:21][CH3:22])(=[O:20])=[O:19])=[C:4]2[C:9](=[CH:10][C:11]=1[Cl:12])[N:8]=[C:7]([O:13]C)[C:6]([O:15]C)=[N:5]2.Cl>O1CCOCC1>[Cl:1][C:2]1[C:3]([N:17]([CH3:23])[S:18]([CH2:21][CH3:22])(=[O:20])=[O:19])=[C:4]2[C:9](=[CH:10][C:11]=1[Cl:12])[NH:8][C:7](=[O:13])[C:6](=[O:15])[NH:5]2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of N-(6,7-dichloro-2,3-dimethoxyquinoxalin-5-yl)-N-(methyl)-ethanesulphonamide (150 mg, 0.39 mmol), 2M hydrochloric acid (4 ml) and dioxane (8 ml) was heated at reflux for 16 hours, cooled, and concentrated under reduced pressure. The solid residue was suspended in water, filtered off, and washed with water and ether to give the title compound (140 mg, 99%) as a white solid, m.p. >300° C.