Diethyl Oxalate → HCID 22097060, compound

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([NH2:8])[C:5]([NH2:9])=[CH:4][C:3]=1[N:10]1[CH:14]=[CH:13][CH:12]=[CH:11]1.[C:15](OCC)(=[O:21])[C:16](OCC)=[O:17]>>[Cl:1][C:2]1[CH:7]=[C:6]2[C:5]([NH:9][C:15](=[O:21])[C:16](=[O:17])[NH:8]2)=[CH:4][C:3]=1[N:10]1[CH:14]=[CH:13][CH:12]=[CH:11]1

Participants

Reactant 2

HCID 7268Diethyl Oxalate

HCID 22097227HCID 22097227, compound

Product 1

HCID 22097060HCID 22097060, compound

Procedure

0.6 g (2.9 mmol) of N-(2-chloro-4,5-diaminophenyl)pyrrole and 32 g (221 mmol) of diethyl oxalate were refluxed for 3 hours. The reaction mixture was cooled and then the crude product was filtered off and washed with petroleum ether.

Workup

temperatureThe reaction mixture was cooled
filtrationthe crude product was filtered off
washwashed with petroleum ether

Sources & evidence

ORD record: ord-6e4f045475d043f795b0a847a31bed80
Source dataset: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05852017

Reaction notes

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