Tetrahydrofuran → HCID 72553275, compound

HRID 146106Notes

Reaction equation

HRID 146106 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH3:30])[c:11]3[c:12]([n:13]2)[s:14][c:15]2[c:16]3[n:17][c:18]([N:24]3[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]3)[n:19][c:20]2[O:21][CH2:22][CH3:23])[cH:6][cH:7]1.[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:31][CH2:32][CH2:33][CH2:34][Li:35].[CH:36]([CH:37]=[CH:38][CH:39]=[CH:40][CH3:41])=[O:42]>>[c:2]1([CH:36]([CH:37]=[CH:38][CH:39]=[CH:40][CH3:41])[OH:42])[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH3:30])[c:11]3[c:12]([n:13]2)[s:14][c:15]2[c:16]3[n:17][c:18]([N:24]3[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]3)[n:19][c:20]2[O:21][CH2:22][CH3:23])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8901Hexa-2,4-dienalHCID 597550637-(4-Bromophenyl)-4-ethoxy-9-methyl-2-piperazin-1-yl-thieno[2,3-d:4,5-d']dipyrimidineHCID 178418339Butyllithium

Product 1

HCID 72553275HCID 72553275, compound

Sources & evidence

ORD record
ord-d30f3601b38a444aae488794a6c0ac83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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