2,6-Difluorobenzoyl isocyanate → Teflubenzuron

HRID 1462014

Reaction equation

HRID 1462014 reaction equation
[F:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[C:3]=1[C:4]([N:6]=[C:7]=[O:8])=[O:5].[F:14][C:15]1[C:21]([Cl:22])=[C:20]([F:23])[C:19]([Cl:24])=[CH:18][C:16]=1[NH2:17]>C1(C)C=CC=CC=1>[F:14][C:15]1[C:21]([Cl:22])=[C:20]([F:23])[C:19]([Cl:24])=[CH:18][C:16]=1[NH:17][C:7]([NH:6][C:4](=[O:5])[C:3]1[C:2]([F:1])=[CH:12][CH:11]=[CH:10][C:9]=1[F:13])=[O:8]

Participants

4

Reactant 2

HCID 27333692,6-Difluorobenzoyl isocyanateHCID 27740003,5-Dichloro-2,4-difluorobenzenamine

Product 1

HCID 91734Teflubenzuron

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Three grams (0.016 mol) of 2,6-difluoro-benzoyl isocyanate were added to a solution of 2.95 gm (0.015 mol) of 2,4-difluoro-3,5-dichloroaniline in 50 ml of toluene. The solution thus obtained was stirred for 15 hours at room temperature. Thereafter, the product which precipitated during that time was removed by suction filtration and dried.

Workup

  1. customThe solution thus obtained
  2. customThereafter, the product which precipitated during that time
  3. customwas removed by suction filtration
  4. customdried

Sources & evidence

ORD record
ord-9bf4f69978b74406ae77f12ebb41fc96
Source dataset
uspto-grants-1984_07
Patent number
US04457943

Linked notes

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