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Tetrahydrofuran → Tert-butyl 3-[5-[tert-butyl(dimethyl)silyl]oxy-1-(3-chlorophenyl)-1-hydroxypentyl]piperidine-1-carboxylate

HRID 146328
Notes
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Reaction equation

HRID 146328 reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[Si:27]([CH3:28])([CH3:29])[O:30][CH2:31][CH2:32][CH2:33][CH2:34][Cl:35].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[CH:7]2[CH2:8][N:9]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:10][CH2:11][CH2:12]2)[cH:20][cH:21][cH:22]1>>[Cl:1][c:2]1[cH:3][c:4]([C:5]([OH:6])([CH:7]2[CH2:8][N:9]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:10][CH2:11][CH2:12]2)[CH2:34][CH2:33][CH2:32][CH2:31][O:30][Si:27]([C:23]([CH3:24])([CH3:25])[CH3:26])([CH3:28])[CH3:29])[cH:20][cH:21][cH:22]1
ParticipantsSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 3382519tert-Butyl(4-chlorobutoxy)dimethylsilaneHCID 53420072Tert-butyl 3-(3-chlorobenzoyl)piperidine-1-carboxylate

Product 1

HCID 72529606Tert-butyl 3-[5-[tert-butyl(dimethyl)silyl]oxy-1-(3-chlorophenyl)-1-hydroxypentyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-109b00eddd8844adb4c365c7467fa170
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes