Acetone → HCID 19917093, compound
Reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:7]=[C:8]([CH:11]=[CH:12][CH:13]=2)[CH:9]=[O:10])=[CH:2]1.C(=O)([O-])[O-].[K+].[K+].[CH3:20][C:21]([CH3:23])=[O:22]>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:7]=[C:8]([CH:9]([OH:10])[CH2:20][C:21](=[O:22])[CH3:23])[CH:11]=[CH:12][CH:13]=2)=[CH:2]1Participants
4
Procedure
300 mg of 3-(3-thienyl)benzaldehyde was dissolved in 3 ml of acetone, and 441 mg of potassium carbonate was added. The mixture was stirred overnight at s room temperature, and then the solvent was evaporated. The residue was worked up in a customary manner, and purified by medium-pressure liquid chromatography [hexane/ethyl acetate =3/1]to give 1-[3-(3-thienyl)phenyl]-3-oxo-1-butanol as a colorless oil.
Workup
- customthe solvent was evaporated
- custompurified by medium-pressure liquid chromatography [hexane/ethyl acetate =3/1]to