Hydrochloric Acid → HCID 178520551, compound
Reaction equation
[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][CH2:8][C:9]([NH:11][CH:12]2[CH2:18][CH:17]3[N:19](C(OC(C)(C)C)=O)[CH:14]([CH2:15][CH2:16]3)[CH2:13]2)=[O:10])[N:3]=[N:2]1.Cl>O1CCOCC1>[CH:17]12[NH:19][CH:14]([CH2:15][CH2:16]1)[CH2:13][CH:12]([NH:11][C:9](=[O:10])[CH2:8][CH2:7][CH2:6][C:4]1[N:3]=[N:2][NH:1][CH:5]=1)[CH2:18]2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A reaction mixture comprising of tert-butyl 3-(4-(1H-1,2,3-triazol-4-yl)butanamido)-8-azabicyclo[3.2.1]octane-8-carboxylate (401 mg, 1.103 mmol) in dioxane (5 ml) was treated with 4M HCl in dioxane (0.827 ml, 3.31 mmol) and stirred at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure to afford the title compound. The material was taken on to the next step without further purification.