1,4-Butane sultone → 4-(5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridin-7-ium-7-yl)butane-1-sulfonate
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:17]([CH3:19])([CH3:18])[C:16]([CH3:20])=[N:15][C:5]2=[N+:6]([CH2:8][CH2:9][CH2:10]S([O-])(=O)=O)[CH:7]=1.C1C[O:27][S:24](=[O:26])(=[O:25])[CH2:23]C1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:17]([CH3:18])([CH3:19])[C:16]([CH3:20])=[N:15][C:5]2=[N+:6]([CH2:8][CH2:9][CH2:10][CH2:23][S:24]([O-:27])(=[O:26])=[O:25])[CH:7]=1Participants
3
Procedure
Compound 26 is prepared analogously to compound 5 (Example 5), except that 1,4-butanesultone is used as a starting material.
Sources & evidence
- ORD record
- ord-3878c5e07bbe4f49ae84dacd349a9a88
- Source dataset
- uspto-grants-2016_08
- Patent number
- US09408924B2
Reaction notes
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