Ethanol → L-Carnitine Vinpocetine

HRID 1484008

Reaction equation

HRID 1484008 reaction equation
[OH:1][C@H:2]([CH2:8][C:9](=[O:11])[O-:10])[CH2:3][N+:4]([CH3:7])([CH3:6])[CH3:5].[CH3:12][CH2:13][C@:14]12[CH:30]=[C:29]([C:31]([O:33][CH2:34][CH3:35])=[O:32])[N:28]3[C:20]4=[C:21]([CH2:36][CH2:37][N:18]([C@@H:19]14)[CH2:17][CH2:16][CH2:15]2)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][C:27]=13.C(O)C.C(OC(C1C=CC(O)=CC=1)=O)C>OCC(CO)O>[CH3:12][CH2:13][C@:14]12[CH:30]=[C:29]([C:31]([O:33][CH2:34][CH3:35])=[O:32])[N:28]3[C:20]4=[C:21]([CH2:36][CH2:37][N:18]([C@@H:19]14)[CH2:17][CH2:16][CH2:15]2)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][C:27]=13.[OH:1][C@H:2]([CH2:8][C:9](=[O:10])[O-:11])[CH2:3][N+:4]([CH3:7])([CH3:5])[CH3:6]

Participants

6

Reactant 4

HCID 702EthanolHCID 8434EthylparabenHCID 10917(-)-CarnitineHCID 443955Vinpocetine

Product 1

HCID 86298728L-Carnitine Vinpocetine

Reagents, catalysts & solvents 1

HCID 753GlycerolSolvent

Conditions

Temperature
55 °C

Procedure

Process: Take L-carnitine and vinpocetine, add into ethanol and boil to completely dissolution, add ethylparaben and stir, and add defined amount of glycerin and stir uniformly, and then slowly add the solution into glycerinated gelatin substrate to preserve heat for later use. Add polysorbate and stir uniformly, and then slowly stir the solution and add into the said glycerinated gelatin substrate, stir well and preserve the heat at 55° C., and affuse into the membrane, and cool them down.

Workup

  1. dissolutionboil to completely dissolution
  2. additionadd
  3. stirringstir uniformly
  4. additionslowly add the solution
  5. temperatureto preserve heat for later use
  6. stirringslowly stir the solution
  7. additionadd into the
  8. stirringstir well
  9. temperaturecool them down

Sources & evidence

ORD record
ord-6ec5712844be46cdb9bde30eea2ff6f8
Source dataset
uspto-grants-2016_08
Patent number
US09421181B2

Linked notes

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