Pyridoxal hydrochloride → Pyridoxal

HRID 1486476

Reaction equation

HRID 1486476 reaction equation
[CH3:1][C:2]1[C:7]([OH:8])=[C:6]([CH:9]=[O:10])[C:5]([CH2:11][OH:12])=[CH:4][N:3]=1.Cl.C(=O)(O)[O-].[Na+]>O>[CH3:1][C:2]1[N:3]=[CH:4][C:5]([CH2:11][OH:12])=[C:6]([CH:9]=[O:10])[C:7]=1[OH:8]

Participants

4

Reactant 2

HCID 6171Pyridoxal hydrochlorideHCID 516892Sodium Bicarbonate

Product 1

HCID 1050PyridoxalYield 81.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1.016 g (5 mmol) of pyridoxal hydrochloride (Aldrich) was placed in an Erlenmeyer and a solution of 0.456 g sodium bicarbonate (5.4 mmol) in 5 mL water was added. The resulting solution was set aside for some time and crystals precipitated. The thus precipitated crystals were collected by filtration, washed with cold water and dried to afford 0.68 g of the pyridoxal free base (80% yield).

Workup

  1. customprecipitated
  2. filtrationThe thus precipitated crystals were collected by filtration
  3. washwashed with cold water
  4. customdried

Sources & evidence

ORD record
ord-5f302a90dd0744fbba641e2dbf36b42c
Source dataset
uspto-grants-2016_08
Patent number
US09428458B2

Linked notes

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