[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1.Cl.[OH-].[Na+]>[Zn].C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1Ten grams of the abovementioned 3-(3-methoxyphenyl)indole, 700 ml of 6N hydrochloric acid and 300 ml of ethanol were mixed and refluxed while 100 g zinc powder was added in small portions, and then the reflux was continued for 5 hours. The reaction solution was made alkaline with an aqueous sodium hydroxide solution and extracted with chloroform. The resultant extract solution was concentrated to a residue which was then dissolved in diluted hydrochloric acid, and washed with ether. The aqueous layer was made alkaline with sodium hydroxide, extracted with chloroform, and dried and concentrated to obtain 4.9 g of 3-(3-methoxyphenyl)indoline.
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