Hydrochloric Acid → 1-amino-3-[7-(benzyloxy)-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl]-4-hydroxyquinolin-2(1H)-one

HRID 149097

Reaction equation

HRID 149097 reaction equation
[ClH:35].[K+:37].[NH2:1][n:2]1[c:3](=[O:34])[c:4]([C:13](=[O:14])[NH:15][c:16]2[c:17]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:18][c:19]([O:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[cH:20][cH:21]2)[c:5]([OH:12])[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[OH-:36]>>[NH2:1][n:2]1[c:3](=[O:34])[c:4]([C:13]2=[N:33][S:30](=[O:31])(=[O:32])[c:17]3[c:16]([cH:21][cH:20][c:19]([O:22][CH2:23][c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[cH:18]3)[NH:15]2)[c:5]([OH:12])[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 961HydroxideHCID 670640351-amino-N-[2-(aminosulfonyl)-4-(benzyloxy)phenyl]-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

Product 1

HCID 1363584841-amino-3-[7-(benzyloxy)-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl]-4-hydroxyquinolin-2(1H)-one

Sources & evidence

ORD record
ord-63c7aae6ddc143b18b0c81bc440a8193
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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