HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

HCID 178437312, compound → HCID 178437313, compound

HRID 1491086
Notes
Print preview

Reaction equation

HRID 1491086 reaction equation
CCC1(C(=O)Nc2c(F)c(F)c(C(F)(F)F)c(F)c2F)CCC1>CC#N.CC(=O)O.CC(=O)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC[N+](CC)(CC)CC.COc1cc(OC)c2ccccc2n1.F[B-](F)(F)F.O=C(O)O.[K].[Pd]>CCC1(C(=O)Nc2c(F)c(F)c(C(F)(F)F)c(F)c2F)CCC1B1OC(C)(C)C(C)(C)O1
ParticipantsConditionsSources & evidenceReaction notes

Participants

9

Reactant 1

HCID 178437312HCID 178437312, compound

Product 1

HCID 178437313HCID 178437313, compoundYield 82%

Reagents, catalysts & solvents 7

HCID 176Acetic AcidReagentHCID 1424362,4-DimethoxyquinolineReagentHCID 2724277Tetraethylammonium tetrafluoroborateReagentHCID 2733548Bis(pinacolato)diboraneReagentHCID 45051578carbonic acid, potassium saltReagentHCID 58759193palladium(I) acetateCatalystHCID 6342AcetonitrileSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-82ff05646655472fa81d6ceaf128cb86
Source dataset
Borylation dataset from Roche
DOI
10.1002/anie.201509996

Reaction notes

Loading…

On this pageParticipantsConditionsSources & evidenceReaction notes