Methanol → Methyl 3,4-dimethylbenzoate

HRID 1494844

Reaction equation

HRID 1494844 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([OH:7])=[O:6].S(Cl)(Cl)=O.[CH3:16]O>CN(C=O)C>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([O:7][CH3:16])=[O:6]

Participants

5

Reactant 3

HCID 887MethanolHCID 120733,4-Dimethylbenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 520902Methyl 3,4-dimethylbenzoate

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

15.0 g of 3,4-dimethyl benzoic acid, 29.0 ml of thionyl chloride, 100 ml of methanol, and 1 ml of DMF were processed in a similar manner as in Reference Example 14-(1) to give 15.7 g of methyl 3,4-dimethylbenzoate.

Sources & evidence

ORD record
ord-32a1edb7f1014afd8add71ca3675c70e
Source dataset
uspto-grants-1991_06
Patent number
US05026856

Linked notes

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