Trifluoroacetic acid → 2-(5-(4-((1R,2S)-2-amino-3-fluoro-1-hydroxypropyl)phenyl)isoxazol-3-yl)acetonitrile
Reaction equation
[C:1]([CH2:3][C:4]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][C:12]([C@H:15]3[O:19]C(C)(C)[N:17](C(OC(C)(C)C)=O)[C@@H:16]3[CH2:29][F:30])=[CH:11][CH:10]=2)[O:6][N:5]=1)#[N:2].FC(F)(F)C(O)=O>C(Cl)Cl.C1(C)C=CC=CC=1>[NH2:17][C@H:16]([CH2:29][F:30])[C@@H:15]([C:12]1[CH:11]=[CH:10][C:9]([C:7]2[O:6][N:5]=[C:4]([CH2:3][C:1]#[N:2])[CH:8]=2)=[CH:14][CH:13]=1)[OH:19]Participants
5
