Sodium ion → 6-(3-Chloro-4-fluoro-phenyl)-8-ethyl-8-methyl-5-(3-methyl-butyl)-5,6,7,8-tetrahydro-[1,5]naphthyridine-2-carboxylic acid methyl ester

HRID 150497

Reaction equation

HRID 150497 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]2[c:12]([cH:13][cH:14]1)[NH:11][CH:10]([c:15]1[cH:16][c:17]([Cl:22])[c:18]([F:21])[cH:19][cH:20]1)[CH2:9][C:8]2([CH3:23])[CH2:24][CH3:25].[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[H-:26].[I:28][CH2:29][CH2:30][CH:31]([CH3:32])[CH3:33].[Na+:27]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]2[c:12]([cH:13][cH:14]1)[N:11]([CH2:29][CH2:30][CH:31]([CH3:32])[CH3:33])[CH:10]([c:15]1[cH:16][c:17]([Cl:22])[c:18]([F:21])[cH:19][cH:20]1)[CH2:9][C:8]2([CH3:23])[CH2:24][CH3:25]

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 109241-Iodo-3-methylbutaneHCID 166653HydrideHCID 66587522HCID 66587522, compound

Product 1

HCID 665877056-(3-Chloro-4-fluoro-phenyl)-8-ethyl-8-methyl-5-(3-methyl-butyl)-5,6,7,8-tetrahydro-[1,5]naphthyridine-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-cc5285e1a59c4e61a460dbb9b41a583d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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