Toluene → 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride

HRID 150606

Reaction equation

HRID 150606 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[F:8][C:9]([c:10]1[cH:11][cH:12][c:13](-[c:16]2[c:17]([C:22](=[O:23])[OH:24])[cH:18][cH:19][cH:20][cH:21]2)[cH:14][cH:15]1)([F:25])[F:26].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[S:27]([Cl:28])([Cl:29])=[O:30]>>[F:8][C:9]([c:10]1[cH:11][cH:12][c:13](-[c:16]2[c:17]([C:22](=[O:23])[Cl:29])[cH:18][cH:19][cH:20][cH:21]2)[cH:14][cH:15]1)([F:25])[F:26]

Participants

5

Reactant 4

HCID 1140TolueneHCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 552514'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acid

Product 1

HCID 110660004'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride

Sources & evidence

ORD record
ord-a78c03f64a9a4027b660634bd55b230a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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