Bromide ion → Tert-butyl 3-(1-hydroxy-1-phenylheptyl)piperidine-1-carboxylate
Reaction equation
[Br-:22].[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[CH:9]1[CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]1.[CH2:23]([CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[Mg+:29].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([OH:8])([CH:9]1[CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]1)[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]Participants
5
Sources & evidence
- ORD record
- ord-bcd2889176284c82a2f7970c8cff2d8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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