Sodium Ion → 2-(5-chloro-2-fluorophenyl)-4-iodo-5-methyl-6,7-dihydro-5H-cyclopentapyrimidine

Reaction equation

[Cl:1][c:2]1[cH:3][cH:4][c:5]([F:19])[c:6](-[c:8]2[n:9][c:10]3[c:11]([c:12]([OH:14])[n:13]2)[CH:15]([CH3:18])[CH2:16][CH2:17]3)[cH:7]1.[I-:20].[Na+:21].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([F:19])[c:6](-[c:8]2[n:9][c:10]3[c:11]([c:12]([I:20])[n:13]2)[CH:15]([CH3:18])[CH2:16][CH2:17]3)[cH:7]1

Participants

Reactant 4

HCID 923Sodium Ion

HCID 24813Phosphorus oxychloride

HCID 30165Iodide Ion

HCID 178423154HCID 178423154, compound

Product 1

HCID 211043082-(5-chloro-2-fluorophenyl)-4-iodo-5-methyl-6,7-dihydro-5H-cyclopentapyrimidine

Sources & evidence

ORD record: ord-709598a5bf704f2ba67614f5fe981feb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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