Ethanol → HCID 9915090, compound

Reaction equation

[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]([CH3:43])[CH2:10][CH2:11][CH2:12][NH:13][C:14]([C:16]1[N:20]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[C:19]2[CH:39]=[CH:40][CH:41]=[CH:42][C:18]=2[N:17]=1)=[O:15].C(O)C>C(OCC)(=O)C>[ClH:1].[CH3:43][N:9]([CH3:8])[CH2:10][CH2:11][CH2:12][NH:13][C:14]([C:16]1[N:20]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[C:19]2[CH:39]=[CH:40][CH:41]=[CH:42][C:18]=2[N:17]=1)=[O:15]

Participants

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.25 ml) was added to a solution containing N-[3-(dimethylamino)propyl]-1-octadecyl-1H-benzimidazole-2-carboxamide (0.499 g) in ethyl acetate (5 ml) and stirred for 10 minutes at room temperature. The reaction mixture, with ethanol (0.3 ml) and ethyl acetate (1 ml) added thereto, was dissolved by heating and then cooled naturally. The depositing crystals were collected by filtration, thereby yielding the entitled compound (0.419 g) as white solid.