Sodium Azide → HCID 22011940, compound
Reaction equation
CS(O[CH:6]1[CH2:10][O:9][CH:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:7]1)(=O)=O.[N-:17]=[N+:18]=[N-:19].[Na+]>CN(C=O)C.CCOCC>[N:17]([CH:6]1[CH2:10][O:9][CH:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:7]1)=[N+:18]=[N-:19]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
14.7 g (61 mmol) of 4-methanesulfonyloxy-2-phenyltetrahydrofuran and 5.13 g (79 mmol) of sodium azide were heated for 3 hours in 120 ml of DMF at 90° C. After the mixture had cooled, it was diluted with ether, washed with water and saturated NaCl solution, dried and concentrated in vacuo. This gave 9.4 g (quant.) of a colorless oil, which was further reacted directly.
Workup
- temperatureAfter the mixture had cooled
- washwashed with water and saturated NaCl solution
- customdried
- concentrationconcentrated in vacuo
- customThis gave 9.4 g (quant.) of a colorless oil, which was further reacted directly
Sources & evidence
- ORD record
- ord-d8cd42e13c40451fac3bb7b11301f67e
- Source dataset
- uspto-grants-2001_03
- Patent number
- US06207668B1
Reaction notes
Loading…