Dichloromethane → 4-(Aminomethyl)cyclohexan-1-ol

Reaction equation

[Cl:24][CH2:25][Cl:26].[OH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][NH:9][C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][NH2:9])[CH2:6][CH2:7]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 25417625tert-Butyl ((4-hydroxycyclohexyl)methyl)carbamate

Product 1

HCID 148675294-(Aminomethyl)cyclohexan-1-ol

Sources & evidence

ORD record: ord-1ca35fde01744b998131077d9d18061a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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