Hydrochloric Acid → 1,3-dihydro-1-{trans-4-[4-(3-pyridinecarbonyl)piperazin-1-yl]-1-cyclohexyl}-2H-benzimidazol-2-one

HRID 1537985

Reaction equation

HRID 1537985 reaction equation
[C:24]([c:25]1[cH:26][n:27][cH:28][cH:29][cH:30]1)(=[O:31])[Cl:32].[ClH:23].[N:1]1([CH:7]2[CH2:8][CH2:9][CH:10]([n:13]3[c:14](=[O:22])[nH:15][c:16]4[c:17]3[cH:18][cH:19][cH:20][cH:21]4)[CH2:11][CH2:12]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([CH:7]2[CH2:8][CH2:9][CH:10]([n:13]3[c:14](=[O:22])[nH:15][c:16]4[c:17]3[cH:18][cH:19][cH:20][cH:21]4)[CH2:11][CH2:12]2)[CH2:2][CH2:3][N:4]([C:24]([c:25]2[cH:26][n:27][cH:28][cH:29][cH:30]2)=[O:31])[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 82604Nicotinoyl chlorideHCID 214715691,3-dihydro-1-{trans-4-[1-piperazinyl]-1-cyclohexyl}-2H-benzimidazol-2-one

Product 1

HCID 99531121,3-dihydro-1-{trans-4-[4-(3-pyridinecarbonyl)piperazin-1-yl]-1-cyclohexyl}-2H-benzimidazol-2-one

Sources & evidence

ORD record
ord-e217ad61633f45cd9da58d1aff7df118
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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