Isopropanol → 5-Chloro-4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-3-nitropyridin-2-amine

HRID 1539970

Reaction equation

HRID 1539970 reaction equation
[CH:28]([OH:29])([CH3:30])[CH3:31].[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2)[c:11]([F:15])[cH:12][cH:13][cH:14]1.[NH2:16][c:17]1[n:18][cH:19][c:20]([Cl:27])[c:21]([Cl:26])[c:22]1[N+:23](=[O:24])[O-:25]>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][CH2:7][N:8]([c:21]3[c:20]([Cl:27])[cH:19][n:18][c:17]([NH2:16])[c:22]3[N+:23](=[O:24])[O-:25])[CH2:9][CH2:10]2)[c:11]([F:15])[cH:12][cH:13][cH:14]1

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 7357371-((2-Chloro-6-fluorophenyl)methyl)piperazineHCID 468676602-Amino-4,5-dichloro-3-nitropyridine

Product 1

HCID 578972505-Chloro-4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-3-nitropyridin-2-amine

Sources & evidence

ORD record
ord-9db7db1d6a69436b87901cd78799cff0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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