Hydrochloric Acid → 4-(2-Chloro-5-methoxyanilino)-2-phenyl-6-(trifluoromethyl)pyrimidine
Reaction equation
[CH2:31]([OH:32])[CH3:33].[Cl:19][c:20]1[c:21]([NH2:22])[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]1.[Cl:1][c:2]1[n:3][c:4](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[ClH:18].[Na+:30].[OH-:29].[OH2:34]>>[c:2]1([NH:22][c:21]2[c:20]([Cl:19])[cH:26][cH:25][c:24]([O:27][CH3:28])[cH:23]2)[n:3][c:4](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
8
Sources & evidence
- ORD record
- ord-cffde13b51a642fa8a1b992e864a184e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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