Dichloromethane → 3-[4-(2-phenyl-9H-imidazo[1,2-d]pyrido[2,3-b][1,4]benzodiazepin-3-yl)phenyl]oxetan-3-amine
Reaction equation
[Cl:50][CH2:51][Cl:52].[OH:43][C:44]([C:45]([F:46])([F:47])[F:48])=[O:49].[c:1]1(-[c:7]2[n:8][c:9]3[n:10]([c:24]2-[c:25]2[cH:26][cH:27][c:28]([C:31]4([NH:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:32][O:33][CH2:34]4)[cH:29][cH:30]2)-[c:11]2[c:12]([n:20][cH:21][cH:22][cH:23]2)[NH:13][c:14]2[c:15]-3[cH:16][cH:17][cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][c:9]3[n:10]([c:24]2-[c:25]2[cH:26][cH:27][c:28]([C:31]4([NH2:35])[CH2:32][O:33][CH2:34]4)[cH:29][cH:30]2)-[c:11]2[c:12]([n:20][cH:21][cH:22][cH:23]2)[NH:13][c:14]2[c:15]-3[cH:16][cH:17][cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
4
Sources & evidence
- ORD record
- ord-14760a6ecd0e48d79cd876b6716b0197
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)