Ethanol → 7-Amino-2-[2-(ethoxycarbonyl)ethyl]-1-methyl-1,2,3,4-tetrahydroisoquinoline

Reaction equation

[C:29](=[O:30])([OH:31])[O-:32].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH2:6][CH2:7][N:8]1[CH:9]([CH3:21])[c:10]2[cH:11][c:12]([N+:18]([O-:19])=[O:20])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1.[CH3:34][CH2:35][OH:36].[Na+:33].[OH2:22].[OH2:23].[Sn:24]([Cl:25])([Cl:26])([Cl:27])[Cl:28]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH2:6][CH2:7][N:8]1[CH:9]([CH3:21])[c:10]2[cH:11][c:12]([NH2:18])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1

Participants

Reactant 6

HCID 702Ethanol

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 962Water2×

HCID 24287Tin tetrachloride

HCID 190671742-[2-(Ethoxycarbonyl)ethyl]-1-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 19067182

Sources & evidence

ORD record: ord-3cac145bf32d421d88169df1207dbdac
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…