Chloroform → [(4-t-Butoxycarbonylamino-butyl)-propyl-amino]-acetic acid ethyl ester

Reaction equation

[Br:24][CH2:25][C:26](=[O:27])[O:28][CH2:29][CH3:30].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][NH:12][CH2:13][CH2:14][CH3:15])=[O:16].[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH:31]([Cl:32])([Cl:33])[Cl:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]([CH2:13][CH2:14][CH3:15])[CH2:25][C:26](=[O:27])[O:28][CH2:29][CH3:30])=[O:16]

Participants

Reactant 4

HCID 6212Chloroform

HCID 7748Ethyl bromoacetate

HCID 8471Triethylamine

HCID 86071285(4-Propylamino-butyl)-carbamic acid t-butyl ester

Product 1

HCID 86614915[(4-t-Butoxycarbonylamino-butyl)-propyl-amino]-acetic acid ethyl ester

Sources & evidence

ORD record: ord-569f3ed02d12407d9b88ac98c8edc9a9
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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