Bromobenzene → 2-(3-Bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine

Reaction equation

[BH:20]([OH:21])[OH:22].[Br:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[Cl:1][c:2]1[n:3][c:4]([C:16]([F:17])([F:18])[F:19])[cH:5][c:6](-[c:8]2[cH:9][c:10]([Cl:15])[c:11]([Cl:14])[cH:12][cH:13]2)[n:7]1>>[c:2]1(-[c:28]2[cH:27][cH:26][cH:25][c:24]([Br:23])[cH:29]2)[n:3][c:4]([C:16]([F:17])([F:18])[F:19])[cH:5][c:6](-[c:8]2[cH:9][c:10]([Cl:15])[c:11]([Cl:14])[cH:12][cH:13]2)[n:7]1

Participants

Reactant 3

HCID 7961Bromobenzene

HCID 61668Boronic Acid

HCID 154777402-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine

Product 1

HCID 574687552-(3-Bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine

Sources & evidence

ORD record: ord-424b7bb07de44cdaa7556d5e05d702f2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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