Ethanol → 3-Carbamoyl-1-(4-chlorobenzyl)piperidine

HRID 1546919

Reaction equation

HRID 1546919 reaction equation
[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:31][C:32]#[N:33].[CH3:34][CH2:35][OH:36].[Cl:17][c:18]1[cH:19][cH:20][c:21]([CH2:22][Cl:23])[cH:24][cH:25]1.[NH2:1][C:2](=[O:3])[CH:4]1[CH2:5][CH2:6][CH2:7][NH:8][CH2:9]1.[Na+:30].[O-:26][C:27]([OH:28])=[O:29].[OH2:37]>>[NH2:1][C:2](=[O:3])[CH:4]1[CH2:5][CH2:6][CH2:7][N:8]([CH2:22][c:21]2[cH:20][cH:19][c:18]([Cl:17])[cH:25][cH:24]2)[CH2:9]1

Participants

9

Reactant 8

HCID 702EthanolHCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 6342AcetonitrileHCID 77231-Chloro-4-(chloromethyl)benzeneHCID 8471TriethylamineHCID 929803-Piperidinecarboxamide

Product 1

HCID 28457973-Carbamoyl-1-(4-chlorobenzyl)piperidine

Sources & evidence

ORD record
ord-9e60a264189849aba86435a76e95da3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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