Phosphorus oxychloride → 7-[3-(Trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Reaction equation
[F:1][C:2]([c:3]1[cH:4][c:5](-[c:9]2[cH:10][cH:11][n:12][c:13]3[n:14]2[n:15][cH:16][c:17]3[C:18](=[O:19])[NH2:20])[cH:6][cH:7][cH:8]1)([F:21])[F:22].[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[F:1][C:2]([c:3]1[cH:4][c:5](-[c:9]2[cH:10][cH:11][n:12][c:13]3[n:14]2[n:15][cH:16][c:17]3[C:18]#[N:20])[cH:6][cH:7][cH:8]1)([F:21])[F:22]Participants
3
Sources & evidence
- ORD record
- ord-ebcfe2fce3654a7f845c6963f7436542
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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