1-Pyrrolidineethanamine → 4,5-Diphenyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrazole-1-acetamide

Reaction equation

[CH:32]([N:33]([CH:34]([CH3:35])[CH3:36])[CH2:37][CH3:38])([CH3:39])[CH3:40].[NH2:24][CH2:25][CH2:26][N:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[c:1]1(-[c:7]2[cH:8][n:9][n:10]([CH2:18][C:19]([O:21][CH2:20][CH3:22])=[O:23])[c:11]2-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][n:9][n:10]([CH2:18][C:19](=[O:21])[NH:24][CH2:25][CH2:26][N:27]3[CH2:28][CH2:29][CH2:30][CH2:31]3)[c:11]2-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

Reactant 3

HCID 13441-Pyrrolidineethanamine

HCID 81531Diisopropylethylamine

HCID 146995514,5-Diphenyl-1-(ethoxycarbonylmethyl)-pyrazole

Product 1

HCID 146995814,5-Diphenyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrazole-1-acetamide

Sources & evidence

ORD record: ord-4495bdc6865f46cdb3db7812609d7a24
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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