Hydrochloric Acid → 4-Bromo-2-fluoro-1-(isocyanatomethyl)benzene

Reaction equation

[Br:13][c:14]1[cH:15][cH:16][c:17]([CH2:18][NH2:19])[c:20]([F:21])[cH:22]1.[Br:1][c:2]1[cH:3][c:4]([F:10])[c:5]([CH2:6][NH2:7])[cH:8][cH:9]1.[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[Cl:23][C:24]([Cl:25])=[O:26].[ClH:11].[ClH:12]>>[Br:1][c:2]1[cH:3][c:4]([F:10])[c:5]([CH2:6][N:7]=[C:24]=[O:26])[cH:8][cH:9]1

Participants

Reactant 4

HCID 313Hydrochloric Acid2×

HCID 1140Toluene

HCID 6371Phosgene

HCID 3770848(4-Bromo-2-fluorophenyl)methanamine2×

Product 1

HCID 158174014-Bromo-2-fluoro-1-(isocyanatomethyl)benzene

Sources & evidence

ORD record: ord-255856c8b06c4774826c7206e9cfbc57
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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