Dichloromethane → Ethyl 2-(1-benzylpiperidin-4-yl)acetate

Reaction equation

[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[Cl:20][CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[Cl:28][CH2:29][Cl:30].[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH2:5][CH2:6]1>>[N:1]1([CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[CH2:2][CH2:3][CH:4]([CH2:7][C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH2:5][CH2:6]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 7503Benzyl Chloride

HCID 8471Triethylamine

HCID 2760465Ethyl 2-(piperidin-4-yl)acetate

Product 1

HCID 10400444Ethyl 2-(1-benzylpiperidin-4-yl)acetate

Sources & evidence

ORD record: ord-ec6e62e370c04c8ea1993ea9acd608f8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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