Acetonitrile → N-{3-[(2-{[(4-methylpiperazin-1-yl)acetyl]amino}imidazo[1,2-b]pyridazin-6-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide

Reaction equation

[CH3:35][N:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1.[CH3:42][C:43]#[N:44].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[n:7][c:8]2[n:9]([n:10][c:11]([O:14][c:15]3[cH:16][c:17]([NH:21][C:22]([c:23]4[cH:24][c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]4)=[O:33])[cH:18][cH:19][cH:20]3)[cH:12][cH:13]2)[cH:34]1>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[n:7][c:8]2[n:9]([n:10][c:11]([O:14][c:15]3[cH:16][c:17]([NH:21][C:22]([c:23]4[cH:24][c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]4)=[O:33])[cH:18][cH:19][cH:20]3)[cH:12][cH:13]2)[cH:34]1)[N:39]1[CH2:38][CH2:37][N:36]([CH3:35])[CH2:41][CH2:40]1